方仁东
[  来源: | 点击数: 次 | 更新时间:2019-02-17 09:50:49  ]

 

方仁东,男,1983年生,博士,副教授,研究生导师。

 

*学习工作经历:

2014/04 至今,西南大学动物科技学院,副教授,研究生导师;

2014/03 京都大学(日本),基础医学院微生物学专业,博士;

2008/07 西南大学,预防兽医学,硕士;

2005/07 西南大学,动物科技学院动物医学专业,本科。

 

*研究生招生专业及方向:

090602预防兽医学

-01动物微生物学与免疫学

-03兽医公共卫生

 

*主要科研项目及发表论文:

主持国家重点研发计划项目子课题1项(2018)、国家自然科学基金青年基金项目1项(2015)、重庆市科委基础与前沿研究计划重点项目1项(2016)、重庆市科委社会民生科技创新专项2项(2015, 2018)、重庆市留学人员创业创新支持计划项目1项(2017)、中央高校基本科研业务费1项(2015)、西南大学博士科研启动项目1项(2014)。主要发表论文如下:

 

2018年:

[1]        Feng S, Huang Q, Ye C, Wu R, Lei G, Jiang J, Chen T, Peng Y, Fang R*. Syk and JNK signaling pathways are involved in inflammasome activation in macrophages infected with Streptococcus pneumoniae. Biochemical and biophysical research communications, 2018, 507(1-4): 217-222.

[2]        Fang R, Jiang B, Xie J, Wang Z, Liang W, Yang Z, Lin LU, Peng Y, Nie K, Zeng Z, Huang B. An Optimized Multilocus Variable-Number Tandem Repeat Analysis Typing Scheme for Listeria monocytogenes from Three Western Provinces in China. Journal of food protection, 2018, 81(12): 1956-1962.

[3]  Yang W, Phongaran D, Prasertsee T, Fang R, Phuektes P, Angkititrakul S. Molecular epidemiology and antimicrobial resistance of Salmonella spp. isolated from broilers and pigs at slaughterhouses in Thailand and China. Thai J Vet Med, 2018, 48(3): 393-401.

[4]        张婷娟, 巫芮, 方仁东*. 白细胞介素-1α的成熟与分泌机制. 微生物学报, 2018, 58(7): 1151-1157.

[5]        蒋兵, 谢建华, 汪子淳, 梁望旺, 杨泽林, 蔺露, 张婷娟, 彭远义, 聂奎, 方仁东*. 基因分型技术在单核细胞增生性李斯特菌监测溯源上的应用. 浙江农林大学学报, 2018, 35(4): 771-777.

[6]        冯思薇, 陈婷婷, 雷桂花, 蒋佳利, 彭远义, 方仁东*. 炎症小体调控宿主肠道菌群研究进展. 中国预防兽医学报, 2018, 40(10): 971-975.

[7]        雷桂花, 雷泽慧, 巫芮, 蒋兵, 陈玉凤, 杨加朝, 方仁东*, 彭远义*. B型多杀性巴氏杆菌感染诱导NLRP3炎症小体激活及IL-1β分泌. 中国兽医学报, 2018, 38(12): 2316-2321.

[8]   方仁东*, 刘力.《兽医公共卫生学》课程教学内容与教学模式的探索. 西南师范大学学报, 43(3): 166-170.

 

2017年:

[1]        Fang R, Wu R, Du H, Jin M, Liu Y, Lei G, Jiang B, Lei Z, Peng Y, Nie K. Pneumolysin-dependent calpain activation and IL-1α secretion in macrophages infected with Streptococcus pneumoniae. Infection & Immunity, 2017, 85(9): IAI.00201-00217.

[2]        Du H, Wu C, Li C, Fang R, Ma J, Ji J, Li Z, Li N, Peng Y, Zhou Z. Two novel crossprotective antigens for bovine Pasteurella multocida. Molecular medicine reports, 2017, 16(4): 4627-4633.

[3]        巫芮, 聂奎, 方仁东*. 肺炎链球菌溶血素的研究进展. 微生物学报, 2017, 57(3): 333-340.

[4]        方仁东, 雷桂花, 彭远义. 病原体与宿主炎症小体相互作用. 微生物学报, 2017, 57(10): 1421-1433.

 

2016年:

[1]        Du H#, Fang R#, Pan T, Li T, Li N, He Q, Wu R, Peng Y, Zhou Z. Comparative Genomics Analysis of Two Different Virulent Bovine Pasteurella multocida Isolates. International Journal of Genomics, 2016, 2016(10): 1-14.

[2]        方仁东, 巫芮, 申艳娜. 炎性小体中ASC斑点形成机理及调控机制. 微生物学报, 2016, 56(9): 1406-1414.

[3]        方仁东, 雷桂花, 杜慧慧, 彭远义. 多杀性巴氏杆菌毒素的研究进展. 中国兽医学报, 2016, 36(11): 1990-1996.

 

2015年以前部分论文:

[1]        Fang R, Hara H, Sakai S, Hernandez-Cuellar E, Mitsuyama M, Kawamura I, Tsuchiya K. Type I Interferon Signaling Regulates Activation of the Absent in Melanoma 2 Inflammasome during Streptococcus pneumoniae Infection. Infection & Immunity, 2014, 82(6): 2310.

[2]        Tsuchiya K, Hara H, Fang R, Hernandez-Cuellar E, Sakai S, Daim S, Chen X, Dewamitta SR, Qu H, Mitsuyama M, Kawamura I. The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner. European journal of immunology, 2014, 44(12): 3696-3707.

[3]        Yang R, Xi C, Sita DR, Sakai S, Tsuchiya K, Hara H, Shen Y, Qu H, Fang R, Mitsuyama M. The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation. Pathogens & Disease, 2014, 70(1): 51-60.

[4]        Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandezcuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M. Phosphorylation of ASC acts as a molecular switch controlling the formation of speck-like aggregates and inflammasome activity. Nature Immunology, 2013, 14(12): 1247-1255.

[5]        Hernandez-Cuellar E, Tsuchiya K, Hara H, Fang R, Sakai S, Kawamura I, Akira S, Mitsuyama M. Cutting edge: nitric oxide inhibits the NLRP3 inflammasome. Journal of Immunology, 2012, 189(11): 5113-5117.

[6]        Yamamoto T, Hara H, Tsuchiya K, Sakai S, Fang R, Matsuura M, Nomura T, Sato F, Mitsuyama M, Kawamura I. Listeria monocytogenes Strain-Specific Impairment of the TetR Regulator Underlies the Drastic Increase in Cyclic di-AMP Secretion and Beta Interferon-Inducing Ability. Infection & Immunity, 2012, 80(7): 2323-2332.

[7]        Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandesalnemri T, Yang R, Hernandezcuellar E. Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection. Journal of Immunology, 2011, 187(9): 4890-4899.

[8]        Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M. Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes. Journal of Immunology, 2010, 185(2): 1186-1195.

[9]        Fang R, Li X, Hu L, You Q, Li J, Wu J, Xu P, Zhong H, Luo Y, Mei J. Cross-Priming Amplification for Rapid Detection of Mycobacterium tuberculosis in Sputum Specimens. Journal of Clinical Microbiology, 2009, 47(3): 845-847.

[10]      Fang R, Li X, Li J, Wu J, Shen X, Gui X, Deriemer K, Liu L, Mei J, Gao Q. Mixed infections of Mycobacterium tuberculosis in tuberculosis patients in Shanghai, China. Tuberculosis, 2008, 88(5): 469-473.

  

*联系方式:

电话:023-68251196(办);传真:023-68251196

QQ 980909449E-mail: rdfang@swu.edu.cn

通讯地址:重庆市北碚区天生路2号西南大学动物科技学院,400715

 


    



西南大学   动物科技学院   版权所有      地 址:重庆市北碚区天生路2号       邮编:400715

你是第  位访问者         管理登陆      技术支持:重庆威堪科技有限公司
领导信箱